Tobacco Smoke and Alcohol Consumption in Relation to Oral Cancer in Albania

Canga Mimoza; Malagnino Antonio Vito

doi:doi:10.11648/j.ijcoms.20180401.16

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Tobacco Smoke and Alcohol Consumption in Relation to Oral Cancer in Albania

Canga Mimoza, Malagnino Antonio Vito

Published in International Journal of Clinical Oral and Maxillofacial Surgery (Volume 4, Issue 1)

Received: 3 July 2018 Accepted: 17 July 2018 Published: 31 August 2018

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Abstract

Objective: The purpose of this study is to investigate the relationship between tobacco, alcohol and other viruses in increasing the risk of being affected by oral carcinomas. Material and method: In our study the sample was composed by 200 patients, all Albanians. The experiment was conducted in the time period 2014-2018, in Albania. The participants were of the age range 45-75 years old and their average age was 60 years old. The ratio between males and females was 3:1, so 152 of the participants were males and 48 were females. The participants were all tobacco users, but they also had other characteristics such as: being virus carriers. More specifically, 44 patients were HPV carriers, 12 patients were EBV carriers, 16 patients were HIV carriers, 72 patients were alcohol addicted, while the remained 56 patients had no viruses they were only tobacco and marijuana smokers. Results: There were 200 patients who were smokers, so smoking is not excluded in any patient. Smoking was the dominant characteristic among participants, 36% of the patients were smokers and consumed alcohol, which increased the risk for oral carcinomas of both kinds. Based on our findings we claim that 36% of the patients smoked and drank alcohol at the same time, 36% were smokers and virus carriers, while 28% were only smokers. Conclusion: Tobacco smoking causes oral carcinomas in those patients who carry viruses, such as: HPV, HIV and EBV, although they are not regular tobacco users.

Published in	International Journal of Clinical Oral and Maxillofacial Surgery (Volume 4, Issue 1)
DOI	10.11648/j.ijcoms.20180401.16
Page(s)	30-34
Creative Commons	This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.
Copyright	Copyright © The Author(s), 2018. Published by Science Publishing Group

Keywords

Alcohol, Oral Carcinomas, Tobacco, Viruses

References

[1]	Douglas E. Morse, Walter J. Psoter, Deborah Cleveland, Donald Cohen, Mireseyed Mohit-Tabatabai, Diane L. Kosis, and Ellen Eisenberg. Smoking and drinking in relation to oral cancer and oral epithelial dysplasia. Cancer Causes Control. 2007 Nov; 18(9): 919–929.
[2]	Abdoul Hossain Madani, Madhurima Dikshit, Debanshu Bhaduri, Teamur Aghamolaei, Seyed Hamid Moosavy, Ali Azarpaykan. Interaction of Alcohol Use and Specific Types of Smoking on the Development of Oral Cancer. Int J High Risk Behav Addict. 2014 Mar; 3(1): e12120.
[3]	Ummar Mangalath, Sachin Aslam Aslam, Abdul Hafiz Kooliyat Abdul Khadar, Pulikkan George Francis, Muhamed Shaloob Karimbil Mikacha, Jubin Hassan Kalathingal. Recent trends in prevention of oral cancer. J Int Soc Prev Community Dent. 2014 Dec; 4(Suppl 3): S131–S138.
[4]	Xinhua Wang, Ji Xu, Lijuan Wang, Chao Liu, Huiming Wang. The role of cigarette smoking and alcohol consumption in the differentiation of oral squamous cell carcinoma for the males in China. 2015, 11(1): 141-145.
[5]	Ackerman LV. Verrucous carcinoma of the oral cavity. Surgery 1948; 23: 670–678.
[6]	Gross A. J, Lackland D. T. Oral cancer and smokeless tobacco: Literature review and meta-analysis. 1995;21(4): 381-394.
[7]	Sung Hee Lee, Chang-Ryul Lee, Nicole Kristina Rigas, Reuben H. Kim, Mo K. Kang, No-Hee ParkKi-Hyuk Shin. Human papillomavirus 16 (HPV16) enhances tumor growth and cancer stemness of HPV-negative oral/oropharyngeal squamous cell carcinoma cells via miR-181 regulation. 2015; 4:116-125.
[8]	Malay Kumar, Ronak Nanavati, Tapan G Modi, Chintan Dobariya. Oral cancer: Etiology and risk factors: A review. 2016; 12(2): 458-463.
[9]	Ogden GR. Alcohol and oral cancer. Alcohol. 2005 Apr; 35(3):169-73.
[10]	Hari Ram, Jayanta Sarkar, Hemant Kumar, Rituraj Konwar, M. L. B. Bhatt, Shadab Mohammad. Oral Cancer: Risk Factors and Molecular Pathogenesis. J Maxillofac Oral Surg. 2011 Jun; 10(2): 132–137.
[11]	Hong AM, Grulich AE, Jones D. Squamous cell carcinoma of the oropharynx in Australian males induced by human papillomavirus vaccine targets. Vaccine 2010; 28:3269–72. [PubMed]
[12]	Chaturvedi AK, Engels EA, Pfeiffer RM. Human papillomavirus and rising oropharyngeal cancer incidence in the United States. J Clin Oncol 2011; 29:4294–301. [PubMed]
[13]	Frisch M, Biggar RJ, Engels EA, Goedert JJ. Association of cancer with AIDS-related immunosuppression in adults. JAMA 2001; 285:1736–1745.
[14]	Hagensee ME, Cameron JE, Leigh JE, Clark RA. Human papillomavirus infection and disease in HIV-infected individuals. Am J Med Sci 2004; 328:57–63. [PubMed]
[15]	Martel-Renoir D, Grunewald V, Touitou R. Qualitative analysis of the expression of Epstein-Barr virus lytic genes in nasopharyngeal carcinoma biopsies. J Gen Virol 1995; 76:1401–1408. [PubMed]
[16]	Shimakage M, Horii K, Tempaku A. Association of Epstein-Barr virus with oral cancers. Hum Pathol 2002; 33:608–614. [PubMed]
[17]	Shroyer KR, Greer RO, Fankhouser CA, McGuirt WF, Marshall R. Detection of human papillomavirus DNA in oral verrucous carcinoma by polymerase chain reaction. Modern Pathology 1993; 6: 669–672.
[18]	Wong M, Pagano JS, Schiller JT. New Associations of human papillomavirus, simian virus 40, and Epstein-Barr virus with human cancer. J Natl Cancer Inst 2002; 94:1832–1836. [PubMed]
[19]	Michael S. McLemore, Missak Haigentz, Jr., Richard V. Smith, Gerard J. Nuovo, Llucia Alos, Antonio Cardesa, Margaret Brandwein-Gensler. Head and Neck Squamous Cell Carcinomas in HIV-Positive Patients: A Preliminary Investigation of Viral Associations. Head Neck Pathol. 2010 Jun; 4(2): 97–105.
[20]	Mucci L. A, Brooks D. R. Lower use of dental services among long term cigarette smokers. J Epidemiol Community Health 2001; 55:389–393.
[21]	Elena Borreani, Desmond Wright, Sasha Scambler, Jennifer E Gallagher. Minimising barriers to dental care in older people. BMC Oral Health. 2008; 8: 7.
[22]	Hooper SJ, Wilson MJ, Crean SJ. Exploring the link between microorganisms and oral cancer: a systematic review of the literature. Head Neck 2009; 31:1228–1239. [PubMed]
[23]	Moreno-López LA, Esparza-Gómez GC, González-Navarro A, Cerero-Lapiedra R, González-Hernández MJ, Domínguez-Rojas V. Risk of oral cancer associated with tobacco smoking, alcohol consumption and oral hygiene: a case-control study in Madrid, Spain. Oral Oncol 2000; 36:170–174. [PubMed].
[24]	Rosenquist K. Risk factors in oral and oropharyngeal squamous cell carcinoma: a population-based case-control study in southern Sweden. Swed Dent J Suppl 2005; 179:1–66. [PubMed].
[25]	Rothman KJ. Epidemiology of head and neck cancer. Laryngoscope 1978; 88:435–8.
[26]	Urberuaga Erce M. Càncer oral. FMC 2012; 19: 321-330.
[27]	Ramseier CA. Smoking prevention and cessation. Oral Health Prev Dent 2003; 1:427–39. [PubMed].

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APA Style

Canga Mimoza, Malagnino Antonio Vito. (2018). Tobacco Smoke and Alcohol Consumption in Relation to Oral Cancer in Albania. International Journal of Clinical Oral and Maxillofacial Surgery, 4(1), 30-34. https://doi.org/10.11648/j.ijcoms.20180401.16

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ACS Style

Canga Mimoza; Malagnino Antonio Vito. Tobacco Smoke and Alcohol Consumption in Relation to Oral Cancer in Albania. Int. J. Clin. Oral Maxillofac. Surg. 2018, 4(1), 30-34. doi: 10.11648/j.ijcoms.20180401.16

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AMA Style

Canga Mimoza, Malagnino Antonio Vito. Tobacco Smoke and Alcohol Consumption in Relation to Oral Cancer in Albania. Int J Clin Oral Maxillofac Surg. 2018;4(1):30-34. doi: 10.11648/j.ijcoms.20180401.16

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@article{10.11648/j.ijcoms.20180401.16,
  author = {Canga Mimoza and Malagnino Antonio Vito},
  title = {Tobacco Smoke and Alcohol Consumption in Relation to Oral Cancer in Albania},
  journal = {International Journal of Clinical Oral and Maxillofacial Surgery},
  volume = {4},
  number = {1},
  pages = {30-34},
  doi = {10.11648/j.ijcoms.20180401.16},
  url = {https://doi.org/10.11648/j.ijcoms.20180401.16},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ijcoms.20180401.16},
  abstract = {Objective: The purpose of this study is to investigate the relationship between tobacco, alcohol and other viruses in increasing the risk of being affected by oral carcinomas. Material and method: In our study the sample was composed by 200 patients, all Albanians. The experiment was conducted in the time period 2014-2018, in Albania. The participants were of the age range 45-75 years old and their average age was 60 years old. The ratio between males and females was 3:1, so 152 of the participants were males and 48 were females. The participants were all tobacco users, but they also had other characteristics such as: being virus carriers. More specifically, 44 patients were HPV carriers, 12 patients were EBV carriers, 16 patients were HIV carriers, 72 patients were alcohol addicted, while the remained 56 patients had no viruses they were only tobacco and marijuana smokers. Results: There were 200 patients who were smokers, so smoking is not excluded in any patient. Smoking was the dominant characteristic among participants, 36% of the patients were smokers and consumed alcohol, which increased the risk for oral carcinomas of both kinds. Based on our findings we claim that 36% of the patients smoked and drank alcohol at the same time, 36% were smokers and virus carriers, while 28% were only smokers. Conclusion: Tobacco smoking causes oral carcinomas in those patients who carry viruses, such as: HPV, HIV and EBV, although they are not regular tobacco users.},
 year = {2018}
}

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TY - JOUR
T1 - Tobacco Smoke and Alcohol Consumption in Relation to Oral Cancer in Albania
AU - Canga Mimoza
AU - Malagnino Antonio Vito
Y1 - 2018/08/31
PY - 2018
N1 - https://doi.org/10.11648/j.ijcoms.20180401.16
DO - 10.11648/j.ijcoms.20180401.16
T2 - International Journal of Clinical Oral and Maxillofacial Surgery
JF - International Journal of Clinical Oral and Maxillofacial Surgery
JO - International Journal of Clinical Oral and Maxillofacial Surgery
SP - 30
EP - 34
PB - Science Publishing Group
SN - 2472-1344
UR - https://doi.org/10.11648/j.ijcoms.20180401.16
AB - Objective: The purpose of this study is to investigate the relationship between tobacco, alcohol and other viruses in increasing the risk of being affected by oral carcinomas. Material and method: In our study the sample was composed by 200 patients, all Albanians. The experiment was conducted in the time period 2014-2018, in Albania. The participants were of the age range 45-75 years old and their average age was 60 years old. The ratio between males and females was 3:1, so 152 of the participants were males and 48 were females. The participants were all tobacco users, but they also had other characteristics such as: being virus carriers. More specifically, 44 patients were HPV carriers, 12 patients were EBV carriers, 16 patients were HIV carriers, 72 patients were alcohol addicted, while the remained 56 patients had no viruses they were only tobacco and marijuana smokers. Results: There were 200 patients who were smokers, so smoking is not excluded in any patient. Smoking was the dominant characteristic among participants, 36% of the patients were smokers and consumed alcohol, which increased the risk for oral carcinomas of both kinds. Based on our findings we claim that 36% of the patients smoked and drank alcohol at the same time, 36% were smokers and virus carriers, while 28% were only smokers. Conclusion: Tobacco smoking causes oral carcinomas in those patients who carry viruses, such as: HPV, HIV and EBV, although they are not regular tobacco users.
VL - 4
IS - 1
ER -

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Author Information

Canga Mimoza

Department of Public Health, University “Ismail Qemali”, Vlore, Albania
Malagnino Antonio Vito

Department of Endodontics, University “Gabriele D’Annunzio”, Chieti, Italy

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Plain Text BibTeX RIS

APA Style

Canga Mimoza, Malagnino Antonio Vito. (2018). Tobacco Smoke and Alcohol Consumption in Relation to Oral Cancer in Albania. International Journal of Clinical Oral and Maxillofacial Surgery, 4(1), 30-34. https://doi.org/10.11648/j.ijcoms.20180401.16

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ACS Style

Canga Mimoza; Malagnino Antonio Vito. Tobacco Smoke and Alcohol Consumption in Relation to Oral Cancer in Albania. Int. J. Clin. Oral Maxillofac. Surg. 2018, 4(1), 30-34. doi: 10.11648/j.ijcoms.20180401.16

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AMA Style

Canga Mimoza, Malagnino Antonio Vito. Tobacco Smoke and Alcohol Consumption in Relation to Oral Cancer in Albania. Int J Clin Oral Maxillofac Surg. 2018;4(1):30-34. doi: 10.11648/j.ijcoms.20180401.16

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@article{10.11648/j.ijcoms.20180401.16,
  author = {Canga Mimoza and Malagnino Antonio Vito},
  title = {Tobacco Smoke and Alcohol Consumption in Relation to Oral Cancer in Albania},
  journal = {International Journal of Clinical Oral and Maxillofacial Surgery},
  volume = {4},
  number = {1},
  pages = {30-34},
  doi = {10.11648/j.ijcoms.20180401.16},
  url = {https://doi.org/10.11648/j.ijcoms.20180401.16},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ijcoms.20180401.16},
  abstract = {Objective: The purpose of this study is to investigate the relationship between tobacco, alcohol and other viruses in increasing the risk of being affected by oral carcinomas. Material and method: In our study the sample was composed by 200 patients, all Albanians. The experiment was conducted in the time period 2014-2018, in Albania. The participants were of the age range 45-75 years old and their average age was 60 years old. The ratio between males and females was 3:1, so 152 of the participants were males and 48 were females. The participants were all tobacco users, but they also had other characteristics such as: being virus carriers. More specifically, 44 patients were HPV carriers, 12 patients were EBV carriers, 16 patients were HIV carriers, 72 patients were alcohol addicted, while the remained 56 patients had no viruses they were only tobacco and marijuana smokers. Results: There were 200 patients who were smokers, so smoking is not excluded in any patient. Smoking was the dominant characteristic among participants, 36% of the patients were smokers and consumed alcohol, which increased the risk for oral carcinomas of both kinds. Based on our findings we claim that 36% of the patients smoked and drank alcohol at the same time, 36% were smokers and virus carriers, while 28% were only smokers. Conclusion: Tobacco smoking causes oral carcinomas in those patients who carry viruses, such as: HPV, HIV and EBV, although they are not regular tobacco users.},
 year = {2018}
}

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