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The Composite of Bone Marrow Concentrate and Nano-hydroxyapatite as an Alternative to Autologous Bone

Received: 5 August 2019     Accepted: 9 September 2019     Published: 15 June 2020
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Abstract

The aim of this study was to examine the evidence behind the use of the composite of bone marrow concentrate and Nano-hydroxyapatite as an alternative to autologous bone graft in the repair of bony defects. The study was conducted on 14 residual surgical non-continuity defects resulting from enucleation of benign odontogenic cysts. The defects were randomly allocated into two groups according to defect filling as follows: Group A (n=7), the defects were grafted using a composite of bone marrow concentrate (BMC) and Nano-hydroxyapatite granules; Group B (n=7), the defects were grafted using autologous bone graft. Radiographic evaluation was done using Cone beam C. T. scan, immediate, six and twelve months post-operatively to assess the volumetric changes of the grafts along the follow-up period. The results of this study revealed that there was no statistically significant difference (p>0.05) between the two groups regarding the percentage of reduction of the graft volume along the follow-up period. In the light of the radiographic results of this study it can be concluded that the use of composite of bone marrow concentrate (BMC) and Nano-hydroxyapatite granules to reconstruct surgical defects is a reliable alternative to autogenous bone graft.

Published in International Journal of Clinical Oral and Maxillofacial Surgery (Volume 6, Issue 2)
DOI 10.11648/j.ijcoms.20200602.11
Page(s) 20-25
Creative Commons

This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.

Copyright

Copyright © The Author(s), 2020. Published by Science Publishing Group

Keywords

Bone Marrow Concentrate, Autogenous Bone Graft, Nano-hydroxyapatite, Surgical Defects

References
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Cite This Article
  • APA Style

    Mahmoud Abdel Aziz El Fadly, Heba Abdel Wahed Selim, Salah Abdel Fattah Ahmed. (2020). The Composite of Bone Marrow Concentrate and Nano-hydroxyapatite as an Alternative to Autologous Bone. International Journal of Clinical Oral and Maxillofacial Surgery, 6(2), 20-25. https://doi.org/10.11648/j.ijcoms.20200602.11

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    ACS Style

    Mahmoud Abdel Aziz El Fadly; Heba Abdel Wahed Selim; Salah Abdel Fattah Ahmed. The Composite of Bone Marrow Concentrate and Nano-hydroxyapatite as an Alternative to Autologous Bone. Int. J. Clin. Oral Maxillofac. Surg. 2020, 6(2), 20-25. doi: 10.11648/j.ijcoms.20200602.11

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    AMA Style

    Mahmoud Abdel Aziz El Fadly, Heba Abdel Wahed Selim, Salah Abdel Fattah Ahmed. The Composite of Bone Marrow Concentrate and Nano-hydroxyapatite as an Alternative to Autologous Bone. Int J Clin Oral Maxillofac Surg. 2020;6(2):20-25. doi: 10.11648/j.ijcoms.20200602.11

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  • @article{10.11648/j.ijcoms.20200602.11,
      author = {Mahmoud Abdel Aziz El Fadly and Heba Abdel Wahed Selim and Salah Abdel Fattah Ahmed},
      title = {The Composite of Bone Marrow Concentrate and Nano-hydroxyapatite as an Alternative to Autologous Bone},
      journal = {International Journal of Clinical Oral and Maxillofacial Surgery},
      volume = {6},
      number = {2},
      pages = {20-25},
      doi = {10.11648/j.ijcoms.20200602.11},
      url = {https://doi.org/10.11648/j.ijcoms.20200602.11},
      eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ijcoms.20200602.11},
      abstract = {The aim of this study was to examine the evidence behind the use of the composite of bone marrow concentrate and Nano-hydroxyapatite as an alternative to autologous bone graft in the repair of bony defects. The study was conducted on 14 residual surgical non-continuity defects resulting from enucleation of benign odontogenic cysts. The defects were randomly allocated into two groups according to defect filling as follows: Group A (n=7), the defects were grafted using a composite of bone marrow concentrate (BMC) and Nano-hydroxyapatite granules; Group B (n=7), the defects were grafted using autologous bone graft. Radiographic evaluation was done using Cone beam C. T. scan, immediate, six and twelve months post-operatively to assess the volumetric changes of the grafts along the follow-up period. The results of this study revealed that there was no statistically significant difference (p>0.05) between the two groups regarding the percentage of reduction of the graft volume along the follow-up period. In the light of the radiographic results of this study it can be concluded that the use of composite of bone marrow concentrate (BMC) and Nano-hydroxyapatite granules to reconstruct surgical defects is a reliable alternative to autogenous bone graft.},
     year = {2020}
    }
    

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  • TY  - JOUR
    T1  - The Composite of Bone Marrow Concentrate and Nano-hydroxyapatite as an Alternative to Autologous Bone
    AU  - Mahmoud Abdel Aziz El Fadly
    AU  - Heba Abdel Wahed Selim
    AU  - Salah Abdel Fattah Ahmed
    Y1  - 2020/06/15
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    DO  - 10.11648/j.ijcoms.20200602.11
    T2  - International Journal of Clinical Oral and Maxillofacial Surgery
    JF  - International Journal of Clinical Oral and Maxillofacial Surgery
    JO  - International Journal of Clinical Oral and Maxillofacial Surgery
    SP  - 20
    EP  - 25
    PB  - Science Publishing Group
    SN  - 2472-1344
    UR  - https://doi.org/10.11648/j.ijcoms.20200602.11
    AB  - The aim of this study was to examine the evidence behind the use of the composite of bone marrow concentrate and Nano-hydroxyapatite as an alternative to autologous bone graft in the repair of bony defects. The study was conducted on 14 residual surgical non-continuity defects resulting from enucleation of benign odontogenic cysts. The defects were randomly allocated into two groups according to defect filling as follows: Group A (n=7), the defects were grafted using a composite of bone marrow concentrate (BMC) and Nano-hydroxyapatite granules; Group B (n=7), the defects were grafted using autologous bone graft. Radiographic evaluation was done using Cone beam C. T. scan, immediate, six and twelve months post-operatively to assess the volumetric changes of the grafts along the follow-up period. The results of this study revealed that there was no statistically significant difference (p>0.05) between the two groups regarding the percentage of reduction of the graft volume along the follow-up period. In the light of the radiographic results of this study it can be concluded that the use of composite of bone marrow concentrate (BMC) and Nano-hydroxyapatite granules to reconstruct surgical defects is a reliable alternative to autogenous bone graft.
    VL  - 6
    IS  - 2
    ER  - 

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Author Information
  • Department of Oral and Maxillofacial Surgery, Faculty of Dentistry, Ain Shams University, Cairo, Egypt

  • Department of Oral and Maxillofacial Surgery, Faculty of Dentistry, Ain Shams University, Cairo, Egypt

  • Department of Oral and Maxillofacial Surgery, Faculty of Dentistry, Ain Shams University, Cairo, Egypt

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